BDBM26267 RO-154513::Ro15-4513::[3H]Ro15-4513::ethyl 12-azido-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate

SMILES: CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(ccc-21)N=[N+]=[N-]

InChI Key: InChIKey=CFSOJZTUTOQNIA-UHFFFAOYSA-N

Data: 38 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 26267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-4 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-2 [26-512]/gamma-2 [40-467] (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10	-11.5	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-4 (Rat)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-2 [26-512]/gamma-2 [40-467] (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	-11.2	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6 (Rat)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-4 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		10.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-4 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		10.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-6 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		11.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human)	BDBM26267 (RO-154513 | Ro15-4513 | ethyl 12-azido-8-methyl-9-...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair