BDBM262984 (S)-2,3-diamino-N-((1r,4S)-4-(3-sulfamoyl-2-(1H-tetrazol-5-yl)-4-(trifluoromethyl)phenyl)cyclohexyl)propanamide::US9708336, 837

SMILES NC[C@H](N)C(=O)NC1CCC(CC1)c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)C(F)(F)F

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262984   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262984((S)-2,3-diamino-N-((1r,4S)-4-(3-sulfamoyl-2-(1H-te...)
Affinity DataIC50:  21.2nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262984((S)-2,3-diamino-N-((1r,4S)-4-(3-sulfamoyl-2-(1H-te...)
Affinity DataIC50:  2.90nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262984((S)-2,3-diamino-N-((1r,4S)-4-(3-sulfamoyl-2-(1H-te...)
Affinity DataIC50:  8.68nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent