BDBM262998 US9708337, 12::neopentyl 5H-chromeno[3,4-c]pyridin-8-ylcarbamate

SMILES: CC(C)(C)COC(=O)Nc1ccc-2c(OCc3cnccc-23)c1

InChI Key: InChIKey=FPEMHDBRKACSGX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 262998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262998 (US9708337, 12 | neopentyl 5H-chromeno[3,4-c]pyridi...) Show SMILES CC(C)(C)COC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C18H20N2O3/c1-18(2,3)11-23-17(21)20-13-4-5-15-14-6-7-19-9-12(14)10-22-16(15)8-13/h4-9H,10-11H2,1-3H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Co. US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair