BindingDB logo
myBDB logout

BDBM262998 US9708337, 12::neopentyl 5H-chromeno[3,4-c]pyridin-8-ylcarbamate

SMILES: CC(C)(C)COC(=O)Nc1ccc-2c(OCc3cnccc-23)c1

InChI Key: InChIKey=FPEMHDBRKACSGX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 262998   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM262998
PNG
(US9708337, 12 | neopentyl 5H-chromeno[3,4-c]pyridi...)
Show SMILES CC(C)(C)COC(=O)Nc1ccc-2c(OCc3cnccc-23)c1
Show InChI InChI=1S/C18H20N2O3/c1-18(2,3)11-23-17(21)20-13-4-5-15-14-6-7-19-9-12(14)10-22-16(15)8-13/h4-9H,10-11H2,1-3H3,(H,20,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 652n/an/an/an/a7.425



Bristol-Myers Squibb Co.

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US9708337 (2017)


BindingDB Entry DOI: 10.7270/Q29W0HH9
More data for this
Ligand-Target Pair