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BDBM26300 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34

SMILES: CCN(CCCOc1ccc2c(c1)ncnc2Nc3cc(n[nH]3)CC(=O)Nc4cccc(c4)F)CCO

InChI Key: InChIKey=QYZOGCMHVIGURT-UHFFFAOYSA-N

Data: 7 KI  3 IC50  811 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 821 hits for monomerid = 26300   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ABL1 [T315I]


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 2.80E+3n/an/an/a7.425


TBA



Citation and Details
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Ligand-Target Pair
Aurora kinase A


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 590n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Aurora kinase B


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 7.20n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Aurora kinase C


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 4.40n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor UFO


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 390n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 11B


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.20E+3n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 11A


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.00E+3n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 7


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 6.20E+3n/an/an/a7.423


TBA



Citation and Details
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.40E+3n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.80E+3n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor [G719C]


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 120n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 110n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 410n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 8.20n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 [D835H]


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 210n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 [D835Y]


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 670n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 140n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 [N841I]


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 43n/an/an/a7.425


TBA



Citation and Details
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 5


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 160n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Muscle, skeletal receptor tyrosine-protein kinase


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.50E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor alpha


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 38n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 41n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [1-999,M918T]


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 80n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [1-999,M918T]


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 120n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor Tie-1


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 350n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Angiopoietin-1 receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.90E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 500n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Blk


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.50E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Citron Rho-interacting kinase


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 5.70E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 450n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 170n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 2.90E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 8.80E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 3.50E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 510n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 380n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.60E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 20


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.70E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Ankyrin repeat and protein kinase domain-containing protein 1


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.50E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor [1-999,L858R]


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 9.80E+5n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase HCK


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 3.90E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 16


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 6.30E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 1.80E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Srms


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 7.90E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase 36


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 4.60E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Dual specificity protein kinase TTK


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 8.50E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 3.80E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 5.20E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 4.30E+3n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4


(Human)		BDBM26300
PNG
(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)		GoogleScholar
UniChem
n/an/an/a 470n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
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