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BDBM263035 US9708340, 12

SMILES: OC(=O)[C@H]1CCN1C(=O)Nc1cc(Cl)ccc1-c1ccccc1

InChI Key: InChIKey=CFPGMGAOJSUDRW-OAHLLOKOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 263035   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid-binding protein 5 (FABP5)


(Homo sapiens (Human))
BDBM263035
PNG
(US9708340, 12)
Show SMILES OC(=O)[C@H]1CCN1C(=O)Nc1cc(Cl)ccc1-c1ccccc1
Show InChI InChI=1S/C17H15ClN2O3/c18-12-6-7-13(11-4-2-1-3-5-11)14(10-12)19-17(23)20-9-8-15(20)16(21)22/h1-7,10,15H,8-9H2,(H,19,23)(H,21,22)/t15-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent




US Patent US9708340 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM263035
PNG
(US9708340, 12)
Show SMILES OC(=O)[C@H]1CCN1C(=O)Nc1cc(Cl)ccc1-c1ccccc1
Show InChI InChI=1S/C17H15ClN2O3/c18-12-6-7-13(11-4-2-1-3-5-11)14(10-12)19-17(23)20-9-8-15(20)16(21)22/h1-7,10,15H,8-9H2,(H,19,23)(H,21,22)/t15-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 20n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9708340 (2017)

More data for this
Ligand-Target Pair