BDBM263444 US9550741, IV-10

SMILES [O-][N+](=O)c1cccc(NC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nsc4ccccc34)CC2)c1

InChI Key InChIKey=ULGYNCVBFLQVPX-MXVIHJGJSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 263444   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

US Patent
LigandPNGBDBM263444(US9550741, IV-10)
Affinity DataKi:  3.64nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

US Patent
LigandPNGBDBM263444(US9550741, IV-10)
Affinity DataKi:  3.64nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVitamin D3 receptor(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

US Patent
LigandPNGBDBM263444(US9550741, IV-10)
Affinity DataKi:  4.15nMAssay Description:The experiment is carried out by the method according to Journal of Pharmacology and Experimental Therapeutics 2010, 333(1): 328. With [3H]methyl-spi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVitamin D3 receptor(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

US Patent
LigandPNGBDBM263444(US9550741, IV-10)
Affinity DataKi:  4.15nMAssay Description:The experiment is carried out by the method according to Journal of Pharmacology and Experimental Therapeutics 2010, 333(1): 328. With [3H]methyl-spi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

US Patent
LigandPNGBDBM263444(US9550741, IV-10)
Affinity DataKi:  5.01nMpH: 7.7Assay Description:1. Experimental Materials(1) 5-HT2A Cell Transfection:This experiment utilizes the plasmid vector containing the gene of the 5-HT2A receptor protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

US Patent
LigandPNGBDBM263444(US9550741, IV-10)
Affinity DataKi:  9.07nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent