BDBM26371 Aminopyrimidine amide urea, 23a::N-(2-aminopyrimidin-5-yl)-2-methyl-5-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)benzamide

SMILES Cc1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1C(=O)Nc1cnc(N)nc1

InChI Key InChIKey=ROAQTOJEPYCOEK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26371   

TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM26371(N-(2-aminopyrimidin-5-yl)-2-methyl-5-({[3-(trifluo...)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
LigandPNGBDBM26371(N-(2-aminopyrimidin-5-yl)-2-methyl-5-({[3-(trifluo...)
Affinity DataIC50: 587nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
LigandPNGBDBM26371(N-(2-aminopyrimidin-5-yl)-2-methyl-5-({[3-(trifluo...)
Affinity DataIC50: 2.50E+4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM26371(N-(2-aminopyrimidin-5-yl)-2-methyl-5-({[3-(trifluo...)
Affinity DataIC50: 2.50E+4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed