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BDBM26382 4-methyl-1-N-[2-methyl-3-(trifluoromethyl)benzene]-3-N-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)benzene-1,3-dicarboxamide::Aminopyrimidine amide, 19

SMILES: Cc1ccc(cc1C(=O)Nc2cnc(nc2)Nc3ccc(cc3)N4CCN(CC4)C)NC(=O)c5cccc(c5C)C(F)(F)F

InChI Key: InChIKey=YNJXLRWECIJSPA-UHFFFAOYSA-N

Data: 5 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26382   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Human)		BDBM26382
PNG
(4-methyl-1-N-[2-methyl-3-(trifluoromethyl)benzene]...)		GoogleScholar
UniChem
n/an/a 0.800n/an/an/an/a7.522


TBA



Citation and Details
More data for this
Ligand-Target Pair
Angiopoietin-1 receptor


(Human)		BDBM26382
PNG
(4-methyl-1-N-[2-methyl-3-(trifluoromethyl)benzene]...)		GoogleScholar
UniChem
n/an/a>8.30E+3n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Human)		BDBM26382
PNG
(4-methyl-1-N-[2-methyl-3-(trifluoromethyl)benzene]...)		GoogleScholar
UniChem
n/an/a 54n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Human)		BDBM26382
PNG
(4-methyl-1-N-[2-methyl-3-(trifluoromethyl)benzene]...)		GoogleScholar
UniChem
n/an/a 12n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Human)		BDBM26382
PNG
(4-methyl-1-N-[2-methyl-3-(trifluoromethyl)benzene]...)		GoogleScholar
UniChem
n/an/a>2.50E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair