BDBM263991 2-{5-[(4-ethylbenzyl)oxy]- 1H-pyrazol-1-yl}pyridine- 4-carboxylic acid::US10173996, Example 56::US9604961, Example 56::US9714230, 56::US9908865, Example 56
SMILES CCc1ccc(COc2ccnn2-c2cc(ccn2)C(O)=O)cc1
InChI Key InChIKey=MKBWAOCGFREQKS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 263991
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:Inhibition of KDM5A/KDM5B in human ZR-75-1 cells assessed as increase in H3K4me3 level after 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair