BDBM26444 (2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentanedioic acid::MurD inhibitor (compound 38)::naphthalene-N-sulfonyl-D-glu derivative, 17c
SMILES CCCCOc1ccc2cc(ccc2c1)S(=O)(=O)N[C@H](CCC(O)=O)C(O)=O
InChI Key InChIKey=UAGYXJBYAFGRFR-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 26444
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals
Lek Pharmaceuticals
Affinity DataIC50: 2.80E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals
Lek Pharmaceuticals
Affinity DataKd: 1.20E+5nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 123 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals
Lek Pharmaceuticals
Affinity DataKd: 2.10E+5nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 4 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals
Lek Pharmaceuticals