BDBM26444 (2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentanedioic acid::MurD inhibitor (compound 38)::naphthalene-N-sulfonyl-D-glu derivative, 17c

SMILES CCCCOc1ccc2cc(ccc2c1)S(=O)(=O)N[C@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=UAGYXJBYAFGRFR-QGZVFWFLSA-N

Data  2 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26444   

TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26444((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50:  2.80E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26444((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataKd:  1.20E+5nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 123 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26444((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataKd:  2.10E+5nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 4 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26444((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50:  2.80E+5nMMore data for this Ligand-Target Pair