BDBM264531 (7R)-7-[3,5- bis(trifluoromethyl)phenyl]- 4-{[4'-fluoro-2'-methoxy-5'- (1-methylethyl)-4- (trifluoromethyl)biphenyl-2- yl]methyl}-6-oxa-4- azaspiro[2.4]heptan-5-one::US9717714, 19
SMILES COc1cc(F)c(cc1-c1ccc(cc1CN1C(=O)O[C@H](c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C11CC1)C(F)(F)F)C(C)C
InChI Key InChIKey=MQUOQPJVFUUKOZ-AREMUKBSSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 264531
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Affinity DataIC50: 361nMAssay Description:Transfer assays are performed in a 96-well v-bottom polypropylene plate. For the RTA using recombinant CETP (2% RTA), an assay cocktail is prepared w...More data for this Ligand-Target Pair