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BDBM264548 US9718760, C246

SMILES: NNC(=O)C(=O)NCCc1ccc(CO)c(CO)c1

InChI Key: InChIKey=SFKGOSHSXXLMOZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264548   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PAI-1/uPA


(Homo sapiens (Human))
BDBM264548
PNG
(US9718760, C246)
Show SMILES NNC(=O)C(=O)NCCc1ccc(CO)c(CO)c1
Show InChI InChI=1S/C12H17N3O4/c13-15-12(19)11(18)14-4-3-8-1-2-9(6-16)10(5-8)7-17/h1-2,5,16-17H,3-4,6-7,13H2,(H,14,18)(H,15,19)
PDB

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 2.56E+6n/an/an/an/a7.425



University of Michigan

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)


Article DOI: 10.1021/jm0492397
BindingDB Entry DOI: 10.7270/Q2K939HK
More data for this
Ligand-Target Pair