BDBM26472 3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)benzene-1-sulfonamide::3-aminobenzene sulfonamide, 12f

SMILES CN(c1ccc2nc(C)n(C)c2c1)c1ccnc(Nc2cccc(c2)S(N)(=O)=O)n1

InChI Key InChIKey=BOSPJTDRCVFWMR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26472   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50:  63nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50:  1.50E+4nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50:  1.70E+3nMAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50:  2.50E+4nMAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50:  2.60E+4nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed