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BDBM264932 US9718790, I-0968

SMILES: Cc1ccc(Cn2c(=O)n(CCC(O)=O)c(=O)[nH]\c2=N/c2ccc(OCC3CC3)c(Cl)c2)cc1

InChI Key: InChIKey=KRRMRDKGDUBCGJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264932   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM264932
PNG
(US9718790, I-0968)
Show SMILES Cc1ccc(Cn2c(=O)n(CCC(O)=O)c(=O)[nH]\c2=N/c2ccc(OCC3CC3)c(Cl)c2)cc1
Show InChI InChI=1S/C24H25ClN4O5/c1-15-2-4-16(5-3-15)13-29-22(27-23(32)28(24(29)33)11-10-21(30)31)26-18-8-9-20(19(25)12-18)34-14-17-6-7-17/h2-5,8-9,12,17H,6-7,10-11,13-14H2,1H3,(H,30,31)(H,26,27,32)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 107n/an/an/an/a7.5n/a



Shionogi & Co., Ltd

US Patent


Assay Description
Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...


US Patent US9718790 (2017)


Article DOI: 10.1021/jm970615f
BindingDB Entry DOI: 10.7270/Q22809KB
More data for this
Ligand-Target Pair