BDBM26520 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-propylpyrimidine-2,4-diamine::Propargyl inhibitor, 18

SMILES: CCCc1c(c(nc(n1)N)N)C#CCc2cc(ccc2OC)OC

InChI Key: InChIKey=VSWSZIRWLYCVMG-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Bacillus anthracis)	BDBM26520 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-propyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	7.0	25
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Dihydrofolate reductase (Human)	BDBM26520 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-propyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM26520 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-propyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Yeast)	BDBM26520 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-propyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair