BDBM26526 (2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide::BMCL181958 Compound 1::CHEMBL148169::IK682

SMILES: C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO

InChI Key: InChIKey=YDMIPBHQKFOFQW-UHFFFAOYSA-N

Data: 29 KI  10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 26526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Pig)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0600	-13.8	n/a	n/a	n/a	n/a	n/a	7.3	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Pig)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Pig)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Pig)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 33 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrilysin (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrilysin (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrilysin (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-15 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-15 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM26526 (BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...) Show SMILES Show InChI	GoogleScholar	UniChem		3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair