BDBM26554 3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1-thiol::CHEMBL402747::thiol-aryl sulfone, 8b

SMILES: CC#CCOc1ccc(cc1)S(=O)(=O)CCCS

InChI Key: InChIKey=CARKQNSZFCLNKM-UHFFFAOYSA-N

Data: 12 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 26554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		10	-10.8	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	-7.94	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	-7.79	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrilysin (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.50E+3	>-7.56	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrilysin (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil collagenase (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70E+3	-7.52	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil collagenase (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30E+3	-7.02	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM26554 (3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair