BDBM26634 (5Z)-5-[(3-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 12a

SMILES COc1cccc(C=C2SC(O)=NC2=O)c1

InChI Key InChIKey=IPQWMGNQGDHUJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26634   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Medical University of South Carolina

LigandPNGBDBM26634((5Z)-5-[(3-methoxyphenyl)methylidene]-1,3-thiazoli...)
Affinity DataIC50:  650nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM26634((5Z)-5-[(3-methoxyphenyl)methylidene]-1,3-thiazoli...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Medical University of South Carolina

LigandPNGBDBM26634((5Z)-5-[(3-methoxyphenyl)methylidene]-1,3-thiazoli...)
Affinity DataIC50:  40nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed