BDBM26656 5,7,3,4,5-pentahydroxyflavone::5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one

SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1cc(O)c(O)c(O)c1

InChI Key InChIKey=ARSRJFRKVXALTF-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26656   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26656(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Affinity DataIC50:  650nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26656(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Affinity DataIC50:  646nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26656(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26656(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM26656(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of human Neu2 assessed as MuNANA substrate hydrolysis in presence of 0.1% Triton X-100 by discontinuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed