BDBM26665 7,8,4-trihydroxyflavone::7,8-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one::CHEMBL420982

SMILES Oc1ccc(cc1)-c1cc(=O)c2ccc(O)c(O)c2o1

InChI Key InChIKey=HJCIUNMVLYBADX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26665   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26665(7,8,4-trihydroxyflavone | 7,8-dihydroxy-2-(4-hydro...)
Affinity DataIC50:  2.20E+4nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Bu-Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM26665(7,8,4-trihydroxyflavone | 7,8-dihydroxy-2-(4-hydro...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human telomerase from HEK293 cell extracts by Flash-Plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26665(7,8,4-trihydroxyflavone | 7,8-dihydroxy-2-(4-hydro...)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed