BDBM26667 (2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one::(S)-5,7-dihydroxyflavanone::CHEMBL399910

SMILES Oc1cc(O)c2C(=O)C[C@H](Oc2c1)c1ccccc1

InChI Key InChIKey=URFCJEUYXNAHFI-ZDUSSCGKSA-N

Data  6 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26667   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26667((2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzo...)
Affinity DataIC50:  1.07E+5nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26667((2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzo...)
Affinity DataIC50:  1.07E+5nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM26667((2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzo...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using HPPA as substrate after preincubated for 15 min followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM26667((2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzo...)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM26667((2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzo...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of human CYP1A2 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM26667((2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzo...)
Affinity DataIC50:  7.91E+3nMAssay Description:Inhibition of human CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed