BDBM26700 9-benzyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2,3-c][1,2]oxazole-3,4-dione::Isoxazoloquinolinedione, 8

SMILES Oc1c2c(noc2=O)n(Cc2ccccc2)c2cc(Cl)c(F)cc12

InChI Key InChIKey=WRWXDAAODUAFDL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26700   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26700(9-benzyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  36.5nM ΔG°:  -10.0kcal/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26700(9-benzyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  558nM ΔG°:  -8.44kcal/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed