BDBM267194 2-chloro-N-{2-[2-(4,4-difluorocyclohexyl)-1,3-thiazol-5-yl]-2-(4,4-difluoropiperidin-1-yl)ethyl}-6-fluorobenzamide::US10167281, Compound 117::US9718812, 117

SMILES Fc1cccc(Cl)c1C(=O)NCC(N1CCC(F)(F)CC1)c1cnc(s1)C1CCC(F)(F)CC1

InChI Key InChIKey=MZTOXVLDQCUYDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267194   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Axxam

US Patent
LigandPNGBDBM267194(2-chloro-N-{2-[2-(4,4-difluorocyclohexyl)-1,3-thia...)
Affinity DataIC50:  429nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Axxam

US Patent
LigandPNGBDBM267194(2-chloro-N-{2-[2-(4,4-difluorocyclohexyl)-1,3-thia...)
Affinity DataIC50:  429nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent