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BDBM26747 bisarylimidazole derivative, 6::ethyl 6-(2-ethyl-4,5-diphenyl-1H-imidazol-1-yl)hexanoate

SMILES: CCOC(=O)CCCCCn1c(CC)nc(c1-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=RNFWCKGWEMYILB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26747   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM26747
PNG
(bisarylimidazole derivative, 6 | ethyl 6-(2-ethyl-...)
Show SMILES CCOC(=O)CCCCCn1c(CC)nc(c1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C25H30N2O2/c1-3-22-26-24(20-14-8-5-9-15-20)25(21-16-10-6-11-17-21)27(22)19-13-7-12-18-23(28)29-4-2/h5-6,8-11,14-17H,3-4,7,12-13,18-19H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 32n/an/an/an/a9.022



Bristol-Myers Squibb Co.



Assay Description
FAAH Inhibition Assay [3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation countin...


Bioorg Med Chem Lett 17: 3287-91 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.009
BindingDB Entry DOI: 10.7270/Q2R20ZPP
More data for this
Ligand-Target Pair