BDBM2684 3-[3-(dimethylamino)propyl]-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaene-12,14-dione::Bisindolyl deriv. 16::indolocarbazole deriv. 4f
SMILES CN(C)CCCn1c2ccccc2c2c3C(=O)NC(=O)c3c3c4ccccc4[nH]c3c12
InChI Key InChIKey=PZTHAMCOXITDIY-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 2684
Affinity DataIC50: 260nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Laboratoires Glaxo
Laboratoires Glaxo
Affinity DataIC50: 500nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
TargetPhosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform(Oryctolagus cuniculus (rabbit))
Laboratoires Glaxo
Laboratoires Glaxo
Affinity DataIC50: 200nMAssay Description:The activity of PK is measured by its ability to transfer from [gamma-32P]ATP to phosphorylase b.More data for this Ligand-Target Pair