BDBM2691 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::BIM-3::Bisindolyl deriv. 19

SMILES: NCCCn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12

InChI Key: InChIKey=APYXQTXFRIDSGE-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 2691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha (Rat)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Rabbit)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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3-phosphoinositide-dependent protein kinase 1 [51-359] (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.5	30
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3-phosphoinositide-dependent protein kinase 1 [51-359,V143T] (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.5	30
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3-phosphoinositide-dependent protein kinase 1 [51-359,L159M] (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.5	30
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3-phosphoinositide-dependent protein kinase 1 [51-359,A162V] (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	7.5	30
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3-phosphoinositide-dependent protein kinase 1 [51-359,E166D] (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	7.5	30
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3-phosphoinositide-dependent protein kinase 1 [51-359,T222A] (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	7.5	30
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3-phosphoinositide-dependent protein kinase 1 [51-359,V143T,T222A] (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.5	30
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Calcium/calmodulin-dependent protein kinase type II subunit delta (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit delta (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Human)	BDBM2691 (Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair