BDBM269350 (E)-3-(4-((2-(3- fluorophenyl)-6- hydroxybenzo[b] thiophen-3-yl)oxy) phenyl)-acrylic acid::US10058534, 7

SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2cccc(F)c2)cc1

InChI Key InChIKey=NYHKFDHITQDZMI-IZZDOVSWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269350   

TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269350((E)-3-(4-((2-(3- fluorophenyl)-6- hydroxybenzo[b] ...)
Affinity DataIC50:  29nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269350((E)-3-(4-((2-(3- fluorophenyl)-6- hydroxybenzo[b] ...)
Affinity DataIC50:  713nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent