BDBM2695 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::BIM-8::Bisindolylmaleimide VIII::Bisindolylmaleimide deriv. 2b::ROCHE screening, 49::Ro 31-7549

SMILES: Cn1cc(c2c1cccc2)C3=C(C(=O)NC3=O)c4cn(c5c4cccc5)CCCN

InChI Key: InChIKey=UQHKJRCFSLMWIA-UHFFFAOYSA-N

Data: 8 IC50  1 Kd  1 ITC

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 2695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C beta type (Rat)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	7.5	30
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cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	8.5	37
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Protein kinase C beta type (Rat)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	8.5	37
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3-phosphoinositide-dependent protein kinase 1 [51-359] (Human)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.5	30
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Serine/threonine-protein kinase TBK1 (Human)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit delta (Human)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Human)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM2695 (Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair