BDBM269664 (2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-4-methyl-2-pyridinyl)-4H-1,2,4-triazol-3-yl)-3-(5-methyl-2-pyrimidinyl)-2-butanesulfonamide::US10058550, Example 178.0::US10221162, Example 178.0::US9845310, Example 178.0

SMILES COc1cc(C)cc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(C)cn2)n1-c1c(OC)cccc1OC

InChI Key InChIKey=AZBPTKHVKKQVMM-ROUUACIJSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 269664   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269664((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-4-...)
Affinity DataEC50:  0.120nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269664((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-4-...)
Affinity DataEC50:  0.120nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269664((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-4-...)
Affinity DataEC50:  0.120nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent