BDBM269841 (1R,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxypyridin-2-yl)-4H-1,2,4-triazol-3-yl)-1-(5-fluoropyrimidin-2-yl)-1-methoxypropane-2-sulfonamide or (1S,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxypyridin-2-yl)-4H-1,2,4-triazol-3-yl)-1-(5-fluoropyrimidin-2-yl)-1-methoxypropane-2-sulfonamide::US10058550, Example 364.0

SMILES CO[C@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(O)n2)n1-c1c(O)cccc1OC)c1ncc(F)cn1

InChI Key InChIKey=XAULDSWJRDDOHB-HXPMCKFVSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 269841   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269841((1R,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(6-metho...)
Affinity DataEC50:  0.150nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent