BDBM269841 (1R,2R)N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxypyridin-2-yl)-4H-1,2,4-triazol-3-yl)-1-(5-fluoropyrimidin-2-yl)-1-methoxypropane-2-sulfonamide or (1S,2S)N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxypyridin-2-yl)-4H-1,2,4-triazol-3-yl)-1-(5-fluoropyrimidin-2-yl)-1-methoxypropane-2-sulfonamide::US10058550, Example 364.0
SMILES CO[C@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(O)n2)n1-c1c(O)cccc1OC)c1ncc(F)cn1
InChI Key InChIKey=XAULDSWJRDDOHB-HXPMCKFVSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 269841
Affinity DataEC50: 0.150nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair