BDBM270075 (2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-(methylamino)-2-pyridinyl)-4H-1,2,4-triazol-3-yl)-3-(5-fluoro-2-pyrimidinyl)-2-butanesulfonamide::US10058550, Example 641.0::US10221162, Example 641.0::US9845310, Example 641.0

SMILES CNc1cccc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(F)cn2)n1-c1c(OC)cccc1OC

InChI Key InChIKey=VUDREPBWFHBSRA-GJZGRUSLSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 270075   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270075((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-(methylami...)
Affinity DataEC50:  0.140nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270075((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-(methylami...)
Affinity DataEC50:  0.140nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270075((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-(methylami...)
Affinity DataEC50:  0.140nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent