BDBM27087 3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,3-benzodiazol-2-yl]-1H-pyrazol-4-yl}urea::pyrazole-benzimidazole urea analogue, 16

SMILES: O=C(NC1CC1)Nc1c[nH]nc1-c1nc2ccc(CN3CCOCC3)cc2[nH]1

InChI Key: InChIKey=LOLPPWBBNUVNQZ-UHFFFAOYSA-N

Data: 10 IC50  2 Other

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 27087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.0	22
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Aurora kinase B (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.5	22
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM27087 (3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
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