BDBM271306 US10059720, Example 121::US10975091, Example 121

SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(SC2CCCCCC2)ccn1)C(O)=O

InChI Key InChIKey=WVBIVWXUSOUBMN-AZUAARDMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 271306   

TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Astellas Pharma

US Patent
LigandPNGBDBM271306(US10059720, Example 121 | US10975091, Example 121)
Affinity DataIC50:  1.60nMAssay Description:Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM271306(US10059720, Example 121 | US10975091, Example 121)
Affinity DataIC50:  13nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Astellas Pharma

US Patent
LigandPNGBDBM271306(US10059720, Example 121 | US10975091, Example 121)
Affinity DataIC50:  1.60nMAssay Description:IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM271306(US10059720, Example 121 | US10975091, Example 121)
Affinity DataIC50:  13nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent