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BDBM27147 2-[2-methyl-1-(propan-2-yl)azetidin-2-yl]-1H-1,3-benzodiazole-4-carboxamide::benzimidazole carboxamide, 12

SMILES: CC(C)N1CCC1(C)c1nc2cccc(C(N)=O)c2[nH]1

InChI Key: InChIKey=GVDAQOCOWNDZSS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27147   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM27147
PNG
(2-[2-methyl-1-(propan-2-yl)azetidin-2-yl]-1H-1,3-b...)
Show SMILES CC(C)N1CCC1(C)c1nc2cccc(C(N)=O)c2[nH]1
Show InChI InChI=1S/C15H20N4O/c1-9(2)19-8-7-15(19,3)14-17-11-6-4-5-10(13(16)20)12(11)18-14/h4-6,9H,7-8H2,1-3H3,(H2,16,20)(H,17,18)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
42 -9.96n/an/an/an/an/a8.022



Abbott Laboratories



Assay Description
PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...


J Med Chem 52: 514-23 (2009)


Article DOI: 10.1021/jm801171j
BindingDB Entry DOI: 10.7270/Q2DN43CK
More data for this
Ligand-Target Pair