BDBM271626 US10065941, Compound I-127::US9732060, Compound I-127

SMILES: C[C@@H](Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ccccn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(O)=O

InChI Key: InChIKey=SKZQFKBIJUXXCG-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 271626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
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P2X purinoceptor 3 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Rat)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 1 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 2 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 4 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 7 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Human)	BDBM271626 (US10065941, Compound I-127 | US9732060, Compound I...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
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