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BDBM272178 US10065950, Example 19

SMILES: CC(C)N1CC(CO)n2cc(-c3ncc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C1=O

InChI Key: InChIKey=GFUGHZVOBBLGJV-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272178   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
inhibitory activity


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM272178
PNG
(US10065950, Example 19)
Show SMILES CC(C)N1CC(CO)n2cc(-c3ncc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C1=O
Show InChI InChI=1/C22H21F2N3O4S/c1-11(2)26-8-14(10-28)27-9-16(19(29)20(30)18(27)22(26)31)21-25-7-15(32-21)5-12-3-4-13(23)6-17(12)24/h3-4,6-7,9,11,14,28,30H,5,8,10H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 8.10n/an/an/an/an/a25



Japan Tobacco Inc

US Patent


Assay Description
The donor DNA was diluted with TE buffer to 20 nM, of which 50 μL was added to each well of streptavidin-coated black plate (manufactured by PIA...


US Patent US10065950 (2018)


Article DOI: 10.1021/jm9802259
BindingDB Entry DOI: 10.7270/Q2RN39V2
More data for this
Ligand-Target Pair