BDBM272673 2-Amino-N-(1-{8-chloro-5-[3-hydroxy-3- (trifluoromethyl)piperidin-1-yl]imidazo[1,5-a]pyridin-6- yl}ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide trifluoroacetate::US10065963, Example 78B

SMILES C[C@H](NC(=O)c1c(N)nn2cccnc12)c1cc(Cl)c2cn[nH]c2c1N1CCCC(O)(C1)C(F)(F)F

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 272673   

LigandPNGBDBM272673(2-Amino-N-(1-{8-chloro-5-[3-hydroxy-3- (trifluorom...)
Affinity DataIC50: <100nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM272673(2-Amino-N-(1-{8-chloro-5-[3-hydroxy-3- (trifluorom...)
Affinity DataIC50: <500nMAssay Description:To measure the Phosphorylated Ribosomal Protein S6 (RPS6) in cell lysates, THP-1 cells (Human Acute Monocytic Leukemia) are purchased from ATCC (Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM272673(2-Amino-N-(1-{8-chloro-5-[3-hydroxy-3- (trifluorom...)
Affinity DataIC50: <100nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent