BDBM273053 2-[(R)-1-(2-phenoxyacetyl)pyrrolidin-2-yl]-7-(propan-2-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one::US10065972, Example 145
SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)COc1ccccc1
InChI Key InChIKey=UKIFNBKNUVIGHN-MRXNPFEDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273053
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 1.50E+3nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair