BDBM27344 2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::JMC502647 Compound 8::Pyrrolopyridinone, 1

SMILES: O=C1NCCc2[nH]c(cc12)-c1ccncc1

InChI Key: InChIKey=DKXHSOUZPMHNIZ-UHFFFAOYSA-N

Data: 2 KI  59 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 61 hits for monomerid = 27344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk2 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Nek6 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase NIM1 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 4 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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STE20-like serine/threonine-protein kinase (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase TAO3 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division cycle 7-related protein kinase (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	7.9	25
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MAP kinase-activated protein kinase 2 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	171	n/a	n/a	n/a	n/a	7.5	30
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MAP kinase-activated protein kinase 3 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.77E+4	n/a	n/a	n/a	n/a	7.5	30
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MAP kinase-activated protein kinase 5 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	7.5	30
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-5 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-4 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 9 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division cycle 7-related protein kinase (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase N2 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase N1 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase N2 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	7.9	25
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Cyclin-dependent kinase 9 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Human)	BDBM27344 (JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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