BDBM27351 2-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::Pyrrolopyridinone, 5
SMILES Nc1nccc(n1)-c1cc2c(CCNC2=O)[nH]1
InChI Key InChIKey=FMVMPEYKBFJPAD-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 27351
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences
Nerviano Medical Sciences
Affinity DataIC50: 7nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences
Nerviano Medical Sciences
Affinity DataIC50: 7nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora-AMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences
Curated by ChEMBL
Nerviano Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences
Curated by ChEMBL
Nerviano Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 219nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair