BDBM27497 2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide::2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin-2-yl)-acetamide::CHEMBL372303::N-(6-oxo-5,6-dihydro- phenanthridin-2-yl)-N,N-dimethylacetamide::N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE::PJ34

SMILES: CN(C)CC(=O)Nc1ccc2c(c1)-c3ccccc3C(=O)N2

InChI Key: InChIKey=UYJZZVDLGDDTCL-UHFFFAOYSA-N

Data: 41 IC50  2 Kd  1 EC50

PDB links: 14 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 27497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP15 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	382	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP4 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	759	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP12 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP14 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP12 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 [R100H] (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Mouse)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62	n/a	n/a	n/a	n/a	7.8	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	8.0	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	7.8	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP14 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27497 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	479	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair