BDBM275440 1-[7-(aminomethyl)-1-(4- fluorophenyl)-1H-pyrazolo[3,4- c]pyridin-5-yl]-3-[(1R)-1- phenylethyl]urea::US9884048, Example 319

SMILES C[C@@H](NC(=O)Nc1cc2cnn(-c3ccc(F)cc3)c2c(CN)n1)c1ccccc1

InChI Key InChIKey=WICMXXOJZMKQJB-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275440   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275440(1-[7-(aminomethyl)-1-(4- fluorophenyl)-1H-pyrazolo...)
Affinity DataIC50:  516nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent