BDBM275998 US10071974, Example 109::US10577336, Example 109

SMILES Cc1cccn2c(ccc12)C(C)(C)NC(=O)[C@@H]1CNCCO1

InChI Key InChIKey=LFSNBSNKFGBQKS-AWEZNQCLSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 275998   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275998(US10071974, Example 109 | US10577336, Example 109)
Affinity DataEC50:  3.70nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275998(US10071974, Example 109 | US10577336, Example 109)
Affinity DataEC50:  3.70nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent