BDBM27682 5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one::CHEMBL125200::dihydroisoquinolinone, 1

SMILES: Cc1cccc2c1CCNC2=O

InChI Key: InChIKey=RLLZPXDJYADIEU-UHFFFAOYSA-N

Data: 1 KI  8 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 27682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	8.0	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Human)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Human)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Human)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Human)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Mouse)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair