BDBM27709 2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin-1-yl]propyl}-8-methyl-3,4-dihydroquinazolin-4-one::CHEMBL401843::quinazolinone analogue, 1e

SMILES: Cc1cccc2c1N=C(NC2=O)CCC[N@@]3CCC(=CC3)c4ccc(cc4)F

InChI Key: InChIKey=LOFDUAJQRUYHBR-UHFFFAOYSA-N

Data: 5 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 27709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27709 (CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	8.0	23
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					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Mouse)	BDBM27709 (CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	25
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					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Bovine)	BDBM27709 (CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27709 (CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27709 (CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair