BDBM277190 4-(4-fluorophenyl)-7-{[6- (trifluoromethyl)pyrimidin-4-yl]methyl}- 5,6,7,8-tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 11-10

SMILES NC(=O)c1cc(-c2ccc(F)cc2)c2CCN(Cc3cc(ncn3)C(F)(F)F)Cc2n1

InChI Key InChIKey=KTWUUKUDFWVAFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277190   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277190(4-(4-fluorophenyl)-7-{[6- (trifluoromethyl)pyrimid...)
Affinity DataIC50:  7.60E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent