BDBM27817 2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-dihydro-1H-indol-6-yl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-6-fluoro-N-methylbenzamide::pyrrolo[2,3-d]pyrimidine deriv., 40

SMILES: CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12

InChI Key: InChIKey=HZTYDQRUAWIZRE-UHFFFAOYSA-N

Data: 4 IC50  442 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 457 hits for monomerid = 27817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-2 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase BRSK1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
eIF-2-alpha kinase GCN2 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Serine/threonine-protein kinase MRCK gamma (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase kinase 2 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Fibroblast growth factor receptor 3 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Protein kinase C eta type (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit beta (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Death-associated protein kinase 1 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
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Myosin-IIIb (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin receptor (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a
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SRSF protein kinase 2 (Human)	BDBM27817 (2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair