BDBM278845 2[(3R)-3- aminopiperidin-1-yl] N-[3-(difluoromethyl)- 1-methyl-1H-pyrazol- 4-yl]thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 24
SMILES OC(=O)C(F)(F)F.Cn1cc(NC(=O)c2csc3ncc(nc23)N2CCC[C@@H](N)C2)c(n1)C(F)F
InChI Key InChIKey=QPQOVEBKNMJEJF-SBSPUUFOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278845
Affinity DataIC50: 0.200nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair