BDBM279160 5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)methyl]-1-isopropyl-3-methyl-pyrazolo[4,3-b]pyridin-7-amine::US10034861, Example 191::US10512632, Example 191::US10766893, Example S191::US10806718, Example 191::US11026923, Example 191::US11491140, Example 191::US11634416, Example 191

SMILES CCOc1ncccc1CNc1cc(nc2c(C)nn(C(C)C)c12)-c1cccnc1OCC

InChI Key InChIKey=RPFGIRQWMRKNBU-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 279160   

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 10nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 160nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 160nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 160nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 160nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 160nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 160nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 160nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 400nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 400nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 400nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 400nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 400nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 400nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandPNGBDBM279160(5-(2-ethoxy-3-pyridyl)-N-[(2-ethoxy-3-pyridyl)meth...)
Affinity DataIC50: 400nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent