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BDBM279433 US10035760, Example CA-111

SMILES: CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)c1ccccc1C)c1cccc(Cl)c1

InChI Key: InChIKey=RAAVMMDRKBYZJR-NRFANRHFSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279433   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM279433
PNG
(US10035760, Example CA-111)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)c1ccccc1C)c1cccc(Cl)c1
Show InChI InChI=1S/C24H22ClF2N3O4S/c1-15-6-3-4-9-22(15)35(33,34)29-24(32)28-21(12-16-10-18(26)14-19(27)11-16)23(31)30(2)20-8-5-7-17(25)13-20/h3-11,13-14,21H,12H2,1-2H3,(H2,28,29,32)/t21-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.50E+3n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
HIV cell culture assay┐MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...


US Patent US10035760 (2018)


BindingDB Entry DOI: 10.7270/Q2HT2RBW
More data for this
Ligand-Target Pair